Chonluten 20mg

What Chonluten is

Chonluten is a commercial label for the tripeptide Glu-Asp-Gly (EDG): three unmodified L-amino acids with a free amine at the glutamate end and a free acid at the glycine end, averaging about 319 g/mol as the free acid. It is the lightest compound in our short-peptide group and the only one of the tripeptides built without alanine or a basic residue.

The name travels in several spellings, including khonluten, and some older material refers to it as T-34, so matching vendors by name alone is unreliable. Two sequence comparisons are worth keeping in mind. Cartalax (AED) sits just 14 Da away from EDG, a gap small enough to demand a careful look at the mass read-out. Pinealon (EDR) opens with the same Glu-Asp pair but closes on arginine rather than glycine, which puts it about 99 Da heavier and changes its charge completely.

Chonluten 20mg specification

How Chonluten is analyzed

EDG has no hydrophobic side chain anywhere, so it is the most weakly retained sequence in the family and needs a very shallow reverse-phase gradient that starts almost fully aqueous, or it vanishes into the solvent front along with salts. Detection relies on the amide chromophore in the low-UV range, since there is no aromatic ring to register at 280 nm. Two sequence-specific signals are worth watching on the mass spectrum. An N-terminal glutamate can cyclize to pyroglutamate, giving a species 18 Da below the parent, near 301. The Asp-Gly bond at the C-terminal end can also rearrange to an isoaspartate form that shares the parent mass and shows up only as a closely eluting peak.

The reverse-phase HPLC purity measured for Chonluten is displayed on this product page. No lot code is printed on the label; a Chonluten vial is keyed to that measurement by its crimp and cap color.

Research contexts for Chonluten

• Method development for near-void analytes on aqueous-compatible C18 and HILIC columns
• Pyroglutamate formation studies using an N-terminal glutamate model
• Electrophoretic and fluorescence DNA-binding assays with a minimal acidic tripeptide
• Mass-accuracy checks separating EDG from Cartalax (AED)

Chonluten is offered for bench-top in-vitro research and nothing else; it is not meant for any person or animal.

Chonluten questions

Is Chonluten the same compound as Bronchogen?

No. Bronchogen is reported as the tetrapeptide Ala-Glu-Asp-Leu, which carries a hydrophobic leucine. Chonluten has three residues and nothing hydrophobic, so the two differ in mass and in how they hold on a column.

What does a signal about 18 Da below 319 mean?

Most likely the pyroglutamate form, in which the N-terminal glutamate has closed into a ring with loss of water. It is a related species rather than the parent sequence, and it typically elutes later than EDG because the ring removes the charged N-terminal amine.

Why do Chonluten purity figures vary so much between vendors?

For a molecule this polar the number depends heavily on column, gradient and wavelength, since small method changes decide whether early-eluting impurities are resolved at all. Compare the methods before comparing the figures.