What GLP-1/GIP/Glucagon 10mg is
Here the triple receptor agonist peptide from our catalog is offered in a 10 mg vial. The name lists the receptors it is profiled against in cell-free and cell-based pharmacology: GLP-1, GIP and glucagon, three structurally related class B GPCRs that share a peptide-binding extracellular domain. The designation is descriptive nomenclature, and the article on GLP-1, GIP and glucagon naming explains how it separates this compound from single and dual receptor products.
The formula C221H342N46O68 describes a peptide that has been extensively modified from a plain coded sequence. It contains α,α-disubstituted amino acids that are not found in ribosomally made proteins, ends in a primary amide instead of a carboxylic acid, and has a lipid diacid attached to one lysine. Those modifications explain why its mass of 4,731.33 g/mol is higher than an unmodified peptide of similar length would give.
GLP-1/GIP/Glucagon 10mg specification
| Catalog name | GLP-1/GIP/Glucagon |
|---|---|
| Classification | Triple receptor agonist peptide, GLP-1, GIP and glucagon receptors (in-vitro nomenclature) |
| Molecular formula | C221H342N46O68 |
| Molecular mass (average) | 4,731.33 g/mol |
| CAS number | 2381089-83-2 |
| Amount per vial | 10 mg |
| Form | Lyophilized solid in a sealed vial |
| HPLC purity | ≥98% |
| Shelf life (sealed) | 36 months |
How GLP-1/GIP/Glucagon 10mg is analyzed
Large lipidated peptides adsorb to glass, metal surfaces and column frits, so a shrinking main-peak area and ghost peaks in a following blank are common artifacts rather than properties of the sample. Bio-inert flow paths and a blank run after each sample help show which is which. The deconvoluted electrospray spectrum should resolve to an average mass near 4731.3, with the 4+ ion expected close to m/z 1183.8.
Beyond those artifacts, the impurity profile of a heavily modified peptide like this is mostly synthesis-related: sequences lacking one hindered α-methyl residue, incompletely deprotected side chains, and forms missing the lipid modification. Our independent reverse-phase HPLC test of this product is published on this page. The vials themselves bear no lot or batch number, so each vial is linked to that test by its crimp and cap color alone.
Research contexts for GLP-1/GIP/Glucagon 10mg
- Full concentration-response curves at the glucagon receptor alongside GLP-1 and GIP receptor lines
- Receptor internalization and β-arrestin recruitment assays in cultured reporter cells
- Surface-adsorption studies of hydrophobic peptides on different vial and column materials
- Deconvolution and charge-state analysis of large modified peptides by LC-MS
This vial is a reagent for in-vitro and instrumental research and has no place in work involving humans or animals.
GLP-1/GIP/Glucagon 10mg questions
What distinguishes a triple receptor designation from a dual one?
The added glucagon receptor in the name. In practice it marks a separate molecule with its own formula, not an extra ingredient added to GLP-1/GIP.
Does the 10 mg vial contain a different molecule from the 5 mg vial?
No. Both carry CAS 2381089-83-2 and the same formula; the fill amount is the only difference.
Why might a blank run after this sample show a small peak?
Lipidated peptides can adsorb in the flow path and bleed off during the next run. That carryover is an instrument effect and should not be counted against the sample.
Buying GLP-1/GIP/Glucagon 10mg in the USA
We send GLP-1/GIP/Glucagon 10mg from inside the United States with tracking, and orders exceeding $100 qualify for free shipping. Labs with continuing receptor-profiling programs can arrange bulk pricing. Purchases are open only to research institutions, licensed researchers, universities and laboratory R&D departments.
For in-vitro laboratory investigation only. GLP-1/GIP/Glucagon 10mg must not be put to human or veterinary use, and it ships without any preparation or dosing guidance.
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