This is an identity reference. It describes what sermorelin denotes, how it relates to neighbouring compounds in the same catalogue category, and its analytical characteristics. It makes no claim about what the compound does and gives no preparation or handling guidance.
What the name refers to
Sermorelin is the 29-amino-acid N-terminal fragment of human growth hormone-releasing hormone, supplied as the C-terminal amide — conventionally written GRF(1–29)NH2. Unlike the modified analogues sold alongside it, sermorelin carries no amino acid substitutions: the sequence is the native GHRH sequence truncated at residue 29.
That is the cleanest way to hold this category in your head. Sermorelin is the unmodified fragment. The compounds sold as modified GRF(1–29) or CJC-1295 are the same fragment with substitutions at four positions, and the DAC variant adds a further chemical modification on top of those.
Why the distinction matters at the receiving desk
Four products in this category can appear on a catalogue page with names that share most of their characters. Sermorelin, modified GRF(1–29), CJC-1295 and CJC-1295 (DAC) are four different materials with four different molecular weights and four different analyses. Read the full product name, and record the exact name in your experimental notes rather than an abbreviation that could describe any of them.
Analytical characteristics
Chain length. Twenty-nine residues is long enough that peak width and column pore size become relevant considerations. Wide-pore stationary phases generally give better peak shape for peptides in this size range.
C-terminal amide. The amide and the free acid differ by about 1 Da. On a high-resolution instrument that is a clear distinction; on a lower-resolution one it may not be, which is worth knowing when interpreting a reported mass.
Aromatic residues. The GHRH sequence contains tyrosine, so there is genuine absorbance at 280 nm and UV quantification by extinction coefficient is available. Purity assessment should still be run at 214 nm for the reasons that apply generally.
Basic residues and counter-ions. Several arginines and lysines across the chain mean a substantial counter-ion load after reverse-phase purification. Expect a meaningful gap between chromatographic purity and net peptide content, and use the net figure for molarity.
Methionine. Where a methionine is present in a sequence, oxidation to the sulfoxide adds 16 Da and shifts retention earlier. It is a common minor species in peptides of this class and a reason to look at the leading edge of the main peak rather than only its height.
Confirming identity independently
Check the full sequence and the C-terminal form against public chemical databases rather than relying on the name. Our product pages carry compound identity links that run those searches.
What we publish
Sermorelin sits in our GHRH and ghrelin receptor peptides category. Its product page carries an independent reverse-phase HPLC analysis, net peptide content, counter-ion form and vial size. Vials carry no batch or lot numbers and are matched to their published test by crimp and cap colour.
Research use only. All products supplied by Battle Born Peptides are laboratory reference materials for in-vitro research and analytical use by qualified professionals. They are not drugs, foods, dietary supplements, cosmetics or medical devices; they are not approved by the FDA or any other regulator for use in humans or animals; and they are not intended to diagnose, treat, cure, mitigate or prevent any disease, or to affect the structure or any function of the body of humans or animals. Nothing in this article is preparation, handling or dosing guidance. See our full research-use terms.